AP Biology Unit 7 Cheat Sheet: Natural Selection

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AP Biology Unit 7: Natural Selection — Evolution in Action
TLDR (Quick Summary)
Natural selection drives evolution by favoring heritable traits that increase survival or reproduction.
Evolution occurs when allele frequencies change in a population over time.
Hardy-Weinberg equations predict equilibrium (no evolution).
Mechanisms: natural selection, genetic drift, gene flow, mutation, sexual selection.
⚡ Download our AP Biology Unit 7 Cheat Sheet for graphs, formulas, and key mnemonics.
Why Unit 7 Matters
This is one of the most tested units on the AP Biology exam. Natural selection connects everything you’ve learned — genetics, ecology, and molecular biology — into one unifying concept: evolution explains biological diversity.
If you understand how traits spread or disappear over generations, you can handle any question about adaptation, allele frequencies, or population change.
Natural Selection: The Core Idea
Charles Darwin’s insight was simple yet powerful — individuals don’t evolve, populations do.
The Three Requirements for Natural Selection:
Variation: Individuals differ in traits.
Heritability: Traits can be passed to offspring.
Differential Survival/Reproduction: Those with favorable traits leave more offspring.
Mnemonic: “VHS → Variation, Heritability, Selection.”
Result? Over generations, advantageous traits become more common — this is evolution in action.
Evidence for Evolution
AP exams often ask you to connect evidence to mechanisms. Here’s what to know:
Fossils: Show transitional species and gradual change.
Homologous structures: Same origin, different function (bat wing vs human arm).
Analogous structures: Different origin, same function (bird vs insect wing).
Molecular data: DNA/protein similarities indicate relatedness.
Biogeography: Species distribution aligns with continental drift and isolation.
Types of Selection
Directional Selection: favors one extreme (e.g., antibiotic resistance).
Stabilizing Selection: favors average (e.g., human birth weight).
Disruptive Selection: favors both extremes (e.g., rock pocket mice in mixed terrain).
Mnemonic: “D-S-D → Directional, Stabilizing, Disruptive.”
👉 These can be drawn as shifting, narrowing, or splitting bell curves — a favorite AP visual question.
Hardy-Weinberg: The Equation of No Evolution
If nothing changes, allele frequencies stay constant.
Formulas:
p + q = 1
p² + 2pq + q² = 1
p = dominant allele frequency
q = recessive allele frequency
p² = homozygous dominant
2pq = heterozygous
q² = homozygous recessive
Conditions: no mutation, no migration, random mating, large population, no natural selection.
Mnemonic: “M-M-R-L-S → My Mom Raises Large Snacks.”
Mechanisms of Evolution
Natural selection — traits improve survival/reproduction.
Genetic drift — random change (bottleneck or founder effect).
Gene flow — movement of alleles between populations.
Mutation — introduces new variation.
Sexual selection — mates choose based on traits.
Tutor Tip: Always link the mechanism to allele frequency change. AP graders want to see that connection explicitly.
Speciation: How New Species Form
Allopatric speciation: geographic barrier splits populations (e.g., islands).
Sympatric speciation: occurs without a barrier (e.g., polyploidy in plants).
Reproductive isolation: prevents mating or producing fertile offspring.
Mnemonic: “Allo = Apart, Sym = Same.”
Real-World Examples
Peppered moths: dark moths survived better in polluted cities (directional selection).
Darwin’s finches: drought favored birds with larger beaks (natural selection in real time).
Antibiotic resistance: bacteria evolve through selection pressure from medication.
Common Pitfalls
Saying individuals evolve (only populations do).
Forgetting that Hardy-Weinberg represents no evolution.
Confusing gene flow (migration) with drift (random).
Not mentioning allele frequency when defining evolution.
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